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Recombinant Murine RANTES (CCL5)

Recombinant Murine RANTES (CCL5)

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Recombinant Murine RANTES (CCL5)

产品详情

产品编号:QC250-07
产品描述:

RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant Murine RANTES is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

 

 

Synonyms: Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta 

 

 

AA Sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS 

 

 

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10-30 ng/ml. 

 

 

Cross Reactivity:
Bacteria, Human, Leech, Mouse, Rat