细胞因子重组蛋白
Recombinant Human Nesfatin-1
Recombinant Human Nesfatin-1
产品详情
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Originally identified as a hypothalamic neuropeptide, nesfatin-1 is also expressed in other areas of the brain, in pancreatic islets β-cells, gastric endocrine cells, and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Recombinant Human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues.
Source: E.coli
Synonyms: None
AA Sequence: VPIDIDKTKV QNIHPVESAK IEPPDTGLYY DEYLKQVIDV LETDKHFREK LQKADIEEIK SGRLSKELDL VSHHVRTKLD EL
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by an in vivo assay using healthy wild type male mice (C57BL/6J). Mice were treated via intraperitoneal injection once at a dose of 4μg Nesfatin-1/gm of body weight. Significant effects on body weight and food consumption were observed relative to saline-treated controls.
Note:
100μg is the largest vial size for this product.
Larger sizes supplied as multiple 100μg vials.