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Recombinant Murine LIX (CXCL6) (92 a.a.)

Recombinant Murine LIX (CXCL6) (92 a.a.)

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Recombinant Murine LIX (CXCL6) (92 a.a.)

产品详情

产品编号:QC250-17
产品描述:

CXCL6, also known as LIX in mice, is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX, LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that binds to the CXCR1 and CXCR2 receptors. Recombinant Murine LIX is a 9.8 kDa protein containing 92 amino acid residues.

Source: E.coli

 

 

Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2 

 

 

AA Sequence: APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIQKI LGSDKKKAKR NALAVERTAS VQ 

 

 

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml. 

 

 

Cross Reactivity:
Human, Mouse