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Animal-Free Recombinant Human IL-15

Animal-Free Recombinant Human IL-15

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Animal-Free Recombinant Human IL-15

产品详情

产品编号:QCAF-200-15
产品描述:

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.  IL-15 exerts its biological activities primarily on T cells.  It is also essential in the development, survival and activation of NK cells.  Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I.  Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.  Recombinant Human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.

Manufactured using all Animal-Free reagents.

 

 

Source: E.coli

 

 

Synonyms: IL-T 

 

 

AA Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS 

 

 

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. 
 

 

 

Cross Reactivity:
Human, Human + Mouse, Monkey, Mouse