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Recombinant Rat IL-2

Recombinant Rat IL-2

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Recombinant Rat IL-2

产品详情

产品编号:QC400-02
产品描述:

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.  IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response.  IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.  Recombinant Rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues.

Source: E.coli

 

 

Synonyms: T-cell growth factor (TCGF), Aldesleukin 

 

 

AA Sequence: MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM 

 

 

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.4 ng/ml, corresponding to a specific activity of ≥ 2.5 x 106 units/mg. 

 

 

Cross Reactivity:
Mouse, Rat