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Recombinant Human IL-2

Recombinant Human IL-2

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Recombinant Human IL-2

产品详情

产品编号:QC200-02
产品描述:

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.  IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response.  IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.  Recombinant Human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Source: E.coli

 

 

Synonyms: T-cell growth factor (TCGF), Aldesleukin 

 

 

AA Sequence: MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT 

 

 

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. 
 

 

 

Cross Reactivity:
Bacteria, Chicken, Cow, Cow + Mouse, Dog, Human, Human + Mouse, Human + Virus, Leech, Monkey, Mouse, Rat