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Recombinant Human FGF-20

Recombinant Human FGF-20

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Recombinant Human FGF-20

产品详情

产品编号:QC100-41
产品描述:

FGF-20 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through the FGFR 2c and 3c, and is expressed during limb and brain development. Recombinant Human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues.

Source: E.coli

 

 

Synonyms: Fibroblast Growth Factor-20, FGFK 

 

 

AA Sequence: PLAEVGGFLG GLEGLGQQVG SHFLLPPAGE RPPLLGERRS AAERSARGGP GAAQLAHLHG ILRRRQLYCR TGFHLQILPD GSVQGTRQDH SLFGILEFIS VAVGLVSIRG VDSGLYLGMN DKGELYGSEK LTSECIFREQ FEENWYNTYS SNIYKHGDTG RRYFVALNKD GTPRDGARSK RHQKFTHFLP RPVDPERVPE LYKDLLMYT 

 

 

Purity: ≥ 90% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. 

 

 

Note: 

1mg will be provided as 2x500μg.

 

 

Cross Reactivity:
Human, Monkey, Mouse, N/A, Rat