细胞因子重组蛋白

Recombinant Human FGF-10

Recombinant Human FGF-10

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Recombinant Human FGF-10

产品详情

产品编号:QC100-26
产品描述:

FGF-10 is a heparin-binding growth factor that belongs to the FGF family.  Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in adult lungs.  It signals through the FGFR 2b.  Recombinant Human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues.

Source: E.coli

 

 

Synonyms: Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2 

 

 

AA Sequence: MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS 

 

 

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. 

 

 

Note: 

1mg will be provided as 2x500μg.

 

 

Cross Reactivity:
Chicken, Dog, Human, Mouse, N/A, Rat